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Bioinstrumentation and BioMEMS Laboratory

Research Highlight:

Photo

Biosensors produce complex outputs which we interpret using machine learning algorithms. We can then visualize grouping of data based on patterns of biomarkers from the original samples.

PUBLICATIONS (selected, only MEMS and instrumentation/sensors work listed here)

Thank you for taking the time to look through our total published work over many years. This page lists the comprehensive total of all of our published work. We publish in several different discipline areas, and we also provide links to sub-categories of our work for easy reference (listed below).

            To view our published work on non-invasive breath analysis, please click HERE.

            To view our published work on agriculture monitoring, please click HERE.

            To view our published work on micro/nano MEMS, instrumentation and novel sensor development, please click HERE.

            To view our published work on algorithms and data analysis, please click HERE.

MICRO/NANO MEMS, INSTRUMENTATION AND SENSORS PUBLICATIONS

Chew BD, Trinh NN, Koch DT, Borras E, LeVasseur MK, Simms LA, McCartney MM, Gibson P, Kenyon NJ, Davis CE*. (2024) Data-Driven Approach to Modeling Microfabricated Chemical Sensor Manufacturing. Analytical Chemistry 96(1): 364-372. DOI: 10.1021/acs.analchem.3c04394

Fung S, LeVasseur MK, McCartney MM, Gibson P, Pimentel-Contreres R, Fung AG, Chew BS, Rajapakse MY, Chakraborty P, Chevy DA, Koch DT, Davis CE*. (2023) Portable chemical detection platform for on-site monitoring of odorant levels in natural gas. Journal of Chromatography A 1705: 464151. DOI: 10.1016/j.chroma.2023.464151

Schmidt AJ, Zamuruyev KO, LeVasseur MK, Fung ST, Anishchenko IM, Kenyon NJ, Davis CE*. (2023) Stable electrospray signal on a microfabricated glass chip with three-dimensional open edge and tiered depth geometries. Microelectronic Engineering 276: 111997. DOI: 10.1016/j.mee.2023.111997

Rajapakse MY, Pistochini TE, Borras E, McCartney MM, Davis CE*. (2023) Controlled air exchange rate method to evaluate reduction of volatile organic compounds by indoor air cleaners. Chemosphere 313: 137528. DOI: 10.1016/j.chemosphere.2022.137528

Trinh NN, Simms LA, Chew BS, Weinstein AS, LaSaponara V, McCartney MM, Kenyon NJ*, Davis CE*. (2022) Glass-to-glass fusion bonding quality and strength evaluation with time, applied force, and heat. Micromachines 13: 1882. DOI: 10.3390/mi13111892

Chew BS, Pimentel Contreras R, McCartney MM, Borras E, Kenyon NJ, Davis CE*. (2022) A low cost, easy-to-assemble, open-source modular mobile sampler design for thermal desorption analysis of breath and environmental VOCs. Journal of Breath Research 16(3): 036005. DOI: 10.1088/1752-7163/ac6c9f

Fung ST, LeVasseur MK, Rajapakse MY, Chew BS, Fung AG, McCartney MM, Kenyon NJ, Davis CE*. (2022) Battery powered dual-polarity ion detector for trace chemical sensing. Sensors and Actuators A 338: 113442. DOI: doi.org/10.1016/j.sna.2022.113442

Rajapakse MY, Borras E, Fung AG, Yeap D, McCartney MM, Fabia FM, Kenyon NJ, Davis CE*. (2021) An environmental air sampler to evaluate personal exposure to volatile organic compounds. Analyst (accepted, in press) DOI: 10.1039/D0AN01521K

Simms LA, Borras E, Chew BS, McCartney MM, Matsui B, Robinson SK, Kenyon NJ, Davis CE*. (2021) Environmental Sampling of Volatile Organic Compounds during the 2018 Camp Fire in Northern California. Environmental Sciences and Technology 103: 135-147. DOI: 10.1016/j.jes.2020.10.003

Pham S, Yeap D, Escalera G, Basu R, Wu X, Kenyon NJ, Hertz-Picciotto I, Ko M, Davis CE*. (2020) Wearable sensor system to monitor physical activity and the physiological effects of heat exposure. Sensors 20(3): 855. DOI: 10.3390/s20030855

Fung AG, Tan L, Duong T, Schivo M, Delplanque JP, Davis CE*, Kenyon NJ*. (2019) Designing a mobile platform, combination spirometer and exhaled breath monitor. Diagnostics 9(3): 100. DOI: 10.3390/diagnostics9030100

Fung AG, Rajapakse MY, McCartney MM, Falcon AK, Fabia F, Kenyon NJ, Davis CE*. (2019) Wearable environmental monitor to quantify personal ambient volatile organic compound exposures. ACS Sensors 4: 1358-1364. DOI: 10.1021/acssensors.9b00304

Zrodnikov Y, Rajapakse MY, Peirano DJ, Aksenov AA, Kenyon NJ, Davis CE*. (2019) High Asymmetric Longitudinal Field Ion Mobility Spectrometry (HALF-IMS) device for low power mobile chemical separation and detection. Analytical Chemistry 91(9): 5523-5529. DOI: 10.1021/acs.analchem.8b05577

Fung AG, Yamaguchi MS, McCartney MM, Aksenov AA, Pasamontes A, Davis CE*. (2019) SPME-based mobile field device for active sampling of volatiles. Microchemical Journal 146: 407-413. DOI: 10.1016/j.microc.2019.01.012

Hagemann LT, McCartney MM, Fung AG, Peirano DJ, Davis CE*, Mizaikoff B*. (2018) Combining fourier transform infrared spectroscopy and differential mobility spectrometry for advanced vapor phase analysis. Analyst 143(23): 5683-5691. DOI: 10.1039/c8an01192c

Anishchenko I, McCartney MM, Fung AG, Peirano DJ, Schirle MJ, Kenyon NJ, Davis CE*. (2018) Modular and reconfigurable gas chromatography / differential mobility spectrometry (GC/DMS) package for detection of volatile organic compounds (VOCs). International Journal of Ion Mobility Spectrometry (in press)

McCartney MM, Zrodnikov Y, Fung AG, LeVasseur MK, Pedersen JM, Zamuruyev KO, Aksenov AA, Kenyon NJ, Davis CE*. An easy to manufacture micro gas preconcentrator for chemical sensing applications ACS Sensors 2(8): 1167-1174. DOI: 10.1021/acssensors.7b00289

Zamuruyev KO, Zrodnikov Y, Davis CE*. (2016) Photolithography-free laser-patterned HF acid-resistant chromium-polyimide mask for rapid fabrication of microfluidic systems in glass. Journal of Micromechanics and Microengineering 37(1): 015010. DOI: 10.1088/0960-1317/27/1/015010

Zamuruyev KO, Zrodnikov Y, Davis CE*. (2016) Photolithography-free laser-patterned HF acid-resistant chromium-polyimide mask for rapid fabrication of microfluidic systems in glass. Technical Digest: Solid-State Sensors, Actuators, and Microsystems Workshop 2016 Hilton Head, SC, USA. 05-09 JUN 2016. pp. 172-175.

Chen R, Crawford K, Davis CE, Eshani R, Vougioukas S, Upadhyaya S. (2015) The drones are coming. Citrograph 6(4): 18-23. LINK

Franssila S, Davis CE, LeVasseur MK, Cao Z, Yobas L. (2015) Chapter 27: Microfluidics and BioMEMS in Silicon. Handbook of Silicon Based MEMS Materials and Technologies, 2nd Edition (editors Lindroos, Motooka, Franssila, Paulasto-Krockel, Tilli, Airaksinen) pp. 565-582. Elsevier Publishers. ISBN: 978-0-323-29965-7. LINK

Cumeras R, Figueras E, Davis CE, Baumbach JI, Gracia I*. (2015) Review on Ion Mobility Spectrometry. Part 1: Current Instrumentation. Analyst 140: 1376-1390. DOI: 10.1039/C4AN01100G

Cumeras R, Figueras E, Davis CE, Baumbach JI, Gracia I*. (2015) Review on Ion Mobility Spectrometry. Part 2: Hyphenated Methods and Effects of Experimental Parameters. Analyst 140: 1391-1410. DOI: 10.1039/C4AN01101E

Kwan AM§, Fung AG§, Jansen PA, Schivo M, Kenyon NJ, Delplanque JP, Davis CE*. (2015) Personal lung function monitoring device for asthma patients. (§joint first authors) IEEE Sensors 15(4): 2238-2247. DOI: 10.1109/JSEN.2014.2373134

Thuesen L, Pavlovsky I, Fink R*, Pasamontes A, Aksenov AA, Davis CE. (2015) Field deployable VOC analyzer for early detection of citrus pathogens. Citrograph 6(3): 60-63. LINK

Zamuruyev KO, Bardaweel HK, Carron CJ, Kenyon NJ, Brand O, Delplanque JP, Davis CE*. (2014) Continuous droplet removal upon dropwise condensation of humid air on a hydrophobic micropatterned surface. Langmuir 30(33): 10133-10142. DOI: 10.1021/la5004462

Aksenov AA, Pasamontes A, Peirano DJ, Zhao W, Dandekar AM, Fiehn O, Eshani R, Davis CE*. (2014) Detection of Huanglongbing disease using differential mobility spectrometry. Analytical Chemistry 86(5): 2481-2488. DOI: 10.1021/ac403469y

Zrodnikov Y, Zamuruyev K, Pedersen JD, Fung AG, Peirano DJ, Schirle MJ, Panigrahy A, Pasamontes A, Cheung WHK, Aksenov AA, Schivo M, Kenyon NJ, Delplanque JP, Davis CE*. (2013) Design criteria for portable point-of-care breath analysis systems. Proceedings of 17th International Conference on Solid-State Sensors, Actuators and Microsystems 16-20 JUN 2013, Barcelona, Spain. DOI: 10.1109/Transducers.2013.6627096

Straume T*, Loftus DJ, Li J, Coleman MA, Davis CE, McMonigal KA, Piccini M, Singh AK. (2013) Biomarker-detection technologies for comprehensive medical diagnosis during deep-space missions. Recent Patents in Space Biotechnology 3: 13-23. DOI: 10.2174/18776116112029990009

Schivo M, Seichter F, Aksenov AA, Pasamontes A, Peirano DJ, Mizaikoff B, Kenyon NJ, Davis CE*. (2013) Mobile instrumentation platform to distinguish airway disorders. Journal of Breath Research 7(1):017113. DOI: 10.1088/1752-7155/7/1/017113

Bardaweel H, Zamuruyev K, Delplanque JP, Kenyon NJ, Carron C, Brand O, Davis CE*. (2012) Microscale surface energy properties for enhanced surface condensation and sampling of exhaled breath metabolites. Technical Digest: Solid-State Sensors, Actuators, and Microsystems Workshop Editors Mehregany M, Monk DJ. 2012 Hilton Head, SC, USA. 03-07 JUN 2012. pp. 239-242. LINK

Aksenov AA, Kapron J, Davis CE. (2012) Predicting compensation voltage for singly-charged ions in high-field asymmetric waveform ion mobility spectrometry (FAIMS). Journal of The American Society for Mass Spectrometry 23(10): 1794-1798. DOI: 10.1007/s13361-012-0427-6

Zrodnikov Y, Davis CE*. (2012) The highs and lows of FAIMS: predictions and future trends for high field asymmetric waveform ion mobility spectrometry. Journal of Nanomedicine and Nanotechnology Volume 3, Issue 5: e109. DOI: 10.4172/2157-7439.1000e109

Lay-Ekuakille A, Davis CE, Kanoun O, Li Z, Trabacca A. (2012) Editorial: Special Issue on Sensors for noninvasive physiological monitoring. IEEE Sensors Journal 12(3): 413-414. DOI: 10.1109/JSEN.2011.2168299

Bumatay A§, Chan R§, Lauher K§, Kwan AM, Stoltz T, Delplanque JP, Kenyon NJ, Davis CE*. (2012) Coupled mobile phone platform with peak flow meter enables real-time lung function assessment. (§joint first authors) IEEE Sensors Journal 12(3): 685-691. DOI: 10.1109/JSEN.2011.2143403

Panigrahy A, Delplanque JP, Davis CE*. (2012) Chapter 7: Future directions for breath sensors. Integrated Microsystems and Nanotechnology: MEMS, Biological, Photonics and Sensors Platform. (editor K. Iniewski). pp. 171-199. CRC Press, Taylor Francis Group. ISBN: 978-1439836200. LINK

Aksenov AA, Cheung WHK, Zhao W, Bardaweel H, Martinelli F, Fiehn O, Dandekar AM, Davis CE*. (2012) Reagentless detection of citrus pathogens using differential mobility spectrometry. Citrograph 3(2): 54-56. LINK

Schivo M, Akesnov AA, Bardaweel H, Zhao W, Kenyon NJ, Davis CE*. (2011) Building biomarker libraries with novel chemical sensors: correlating differential mobility spectrometer signal outputs with mass spectrometry data. IOP Conference Series: Materials Science and Engineering 18 (2011) 212003 (doi:10.1088/1757-899X/18/21/212003) DOI: 10.1088/1757-899X/18/21/212003

Han H, Bhushan A, Yaghmaie F, Davis CE*. (2010) Direct thermal-UV nanoimprint of an iron-containing organometallic hybrid film. Journal of Vacuum Science and Technology - Part B 28(1): 78-81. DOI: 10.1116/1.3271337

Strand N, Bhushan A, Schivo M, Kenyon N, Davis CE*. (2010) Chemically polymerized polypyrrole for on-chip concentration of volatile breath metabolites. Sensors and Actuators B 143(2): 516-523. DOI: 10.1016/j.snb.2009.09.052

Han H, Bissell J, Yaghmaie F, Davis CE*. (2010) Polymeric acrylate-based hybrid films containing lead and iron patterned by UV photo-polymerization. Langmuir 26(1): 515-520. DOI: 10.1021/la902195k

Davis CE*, Bogan MJ, Sankaran S, Molina MA, Loyola BR, Zhao W, Benner WH, Schivo M, Farquar GR, Kenyon NJ, Frank M. (2010) Volatile and non-volatile analysis of biomarkers in human breath using differential mobility spectrometry. IEEE Sensors Journal special issue "Sensors for Breath Analysis" 10(1): 114-122. DOI: 10.1109/JSEN.2009.2033562

Davis CE*, Frank M*, Mizaikoff B*, Oser H*. (2010) EDITORIAL: The future of sensors and instrumentation for human breath analysis. IEEE Sensors Journal special issue "Sensors for Breath Analysis" 10(1): 3-6. DOI: 10.1109/JSEN.2009.2035675

Bhushan A, Han H, Sutherland A, Boehme S, Yaghmaie F, Davis CE*. (2010) Generation of paramagnetic hybrid inorganic/organic thin films. Applied Organometallic Chemistry 24(7): 530-532. DOI: 10.1002/aoc.1653

Zhao W, Bhushan A, Schivo M, Kenyon NJ, Davis CE*. (2010) Miniature differential mobility spectrometry (DMS) advances towards portable autonomous health diagnostic systems. Wearable and Autonomous Biomedical Devices and Systems: New issues and Characterization. (editors S.C. Mukhopadhyay and A. Lay-Ekuakille) pp. 144-165. Springer-Verlag (Berlin, Heidelberg), ISBN: 978-3-642-05166-1. DOI: 10.1007/978-3-642-15687-8_3

Simon MG, Davis CE*. (2010) Instrumentation and sensors for human breath analysis. Advances in Biomedical Sensing, Measurements, Instrumentation and Systems (eds. S.C. Mukhopadhyay and A. Lay-Ekuakille) pp. 144-165. Springer-Verlag Publishers (Berlin, Heidelberg). ISBN: 978-3-642-05166-1. DOI: 10.1007/978-3-642-05167-8_10

Bhushan A, Davis CE*. (2010) Chapter 29: Silicon based Bio-MEMS Devices: Micromachining Technologies. Handbook of Silicon Based MEMS Materials and Technologies (editors V. Lindroos, M. Tilli, A. Lehto, T. Motooka) pp. 489-498. Elsevier Publishers. ISBN: 978-0-8155-1594-4. LINK

Han H, Sutherland A, Yaghmaie F, Davis CE*. (2009) Development of a lead oxide photopatternable organic-inorganic film. Applied Physics Letters 94(14): 144106. DOI: 10.1063/1.3109798

Yaghmaie F, Nielsen W, Han H, Bhushan A, Davis CE*. (2009) A simplified method to produce a functional test stamp for nanoimprint lithography (NIL). IEEE Sensors Journal 9(3): 233-234. DOI: 10.1109/JSEN.2008.2011963

Katzenmeyer AM, Bayam Y, Logeeswaran VJ, Pitcher MW, Nur Y, Seyyidoglu S, Toppare LK, Talin AA, Han H, Davis CE, Islam MS*. (2009) Poly(hydridocarbyne) as a highly processable insulating polymer precursor to micro/nanostructures and graphite conductors. Journal of Nanomaterials 2009: 1-4. DOI: 10.1155/2009/832327

Molina M, Zhao W, Sankaran S, Schivo M, Kenyon NJ, Davis CE*. (2008) Design-of-experiment optimization of exhaled breath condensate analysis using a miniature differential mobility spectrometer (DMS). Analytica Chimica Acta 628: 155-161. DOI: 10.1016/j.aca.2008.09.010

Katzenmeyer AM, Bayam Y, Logeeswaran VJ, Pitcher MW, Nur Y, Seyyidoglu S, Toppare LK, Talin AA, Han H, Davis CE, Islam MS*. (2008) Poly(hydridocarbyne) as a highly processable insulating polymer precursor to micro/nanostructures and graphite conductors. The 8th International Conference on Nanotechnology 1: 1-3.

Abramowitch S, Cooper R, Dasco C, Davis C, Hampapur A, Mataric M, Peckham H, Wanagat J, Weinrich M, Barron N. (2008) "Develop Technological Interventions to Overcome Barriers to Independence and Community Participation" The National Academies Keck Futures Initiative: The Future of Human Healthspan: Demography, Evolution, Medicine, and Bioengineering, Task Group Summaries. The National Academies Press (Washington, DC), pp. 57-72. ISBN: 10: 0309115590. LINK

Sankaran S, Loyola B, Zhao W, Morgan JT, Molina M, Schivo M, Kenyon NJ, Davis CE*. (2007) Micromachined differential mobility spectrometers for breath analysis. Sensors, 2007 IEEE 1: 16-19. DOI: 10.1109/ICSENS.2007.4388324

Frank M*, Farquar G, Adams C, Bogan M, Martin A, Benner H, Spadaccini C, Steele P, Sankaran S, Loyola B, Morgan J, Davis CE. (2007) Modular sampling and analysis techniques for real-time analysis of human breath. Sensors, 2007 IEEE 1: 10-13. DOI: 10.1109/ICSENS.2007.4388322

Han Huilan, Davis CE*. (2007) Tutorial on chip-based electrophysiology to assess ion channel function. Nanomaterials Synthesis, Interfacing, and Integrating in Devices, Circuits, and Systems II. Proceedings of SPIE 6768(26): 1-10. DOI: 10.1117/12.737200

Krebs MD, Mansfield B, Yip P, Cohen SJ, Sonenshein AL, Hitt B, Davis CE*. (2006) Spore biomarkers differentiate between closely-related Bacillus species using differential mobility spectrometry. Biomolecular Engineering 23(2): 119-127. DOI: 10.1016/j.bioeng.2005.12.003

Morgan JT, Davis CE*. (2006) Differential mobility spectrometry applications in homeland security, clinical diagnostics and drug discovery. 2006 ASME International Mechanical Engineering Congress and Exposition. November 5-10, 2006, Chicago, Illinois. IMECE2006-15937.

Shnayderman M, Mansfield B, Yip P, Clark HA, Krebs MD, Cohen SJ, Zeskind JE, Ryan ET, Dorkin HL, Callahan MV, Stair TO, Gelfand JA, Gill CJ, Hitt B, Davis CE*. (2005) Species-specific bacteria identification using differential mobility spectrometry and bioinformatics pattern recognition. Analytical Chemistry 77(18): 5930-5937. DOI: 10.1021/ac050348i

Krebs MD, Zapata AM, Nazarov EG, Miller RA, Costa IS, Sonenshein AL, Davis CE*. (2005) Detection of biological and chemical agents using differential mobility spectrometry (DMS). IEEE Sensors Journal, Special Edition on Anti-Terrorism 5(4): 696-703. DOI: 10.1109/JSEN.2005.845515

Davis CE, Rychak JJ, Hosticka B, Davis SC, John JE, Norris PM, Moorman JR*. (2004) A novel technique to measure dynamic cell volume changes. Journal of Applied Physiology 96(5): 1886-1893. DOI: 10.1152/japplphysiol.00268.2003

Davis CE*, Kang JM, Dube CE, Borenstein JT, Nazarov EG, Miller RA, Zapata AM. (2003) Spore biomarker detection using a MEMS Differential Mobility Spectrometer. The 12th IEEE International Conference on Solid-State Sensors and Microsystems Conference, IEEE Proceedings Vol 2: 1233-1238. DOI: 10.1109/SENSOR.2003.1216995

Blain-Christen JM, Davis CE, Li M, Andreou AG*. (2002) Robust Polymeric Techniques for Design, Post-processing and Packaging Arrays of Bio-MEMS Devices. Proceedings from The Tenth Meeting of the Symposium on Polymers for Microelectronics. Vol 1: 700-703.

Blain-Christen JM, Davis CE, Li M, Andreou AG*. (2002) Design, double sided post-processing, and packaging of CMOS compatible bio-MEMS device arrays. Circuits and Systems, 2002. ISCAS 2002. IEEE International Symposium on Circuits and Systems. Vol 1: 665-668.